CRACR2A Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-19269-20UL
60 ul
£183,00
E-AB-19269-60UL
120 ul
£272,00
E-AB-19269-120UL
200 ul
£420,00
E-AB-19269-200UL
Über dieses Produkt
- SKU:
- E-AB-19269
- Zusätzliche Namen:
- CRAC channel regulator 2A;CRACR2A;Calcium release-activated calcium channel regulator 2A;EF hand calcium binding domain 4B;EF hand calcium binding domain containing protein 4B;EF-hand calcium-binding domain-containing protein 4B;EFC4B;EFCAB 4B;Efcab4b;FLJ
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.84 mg/ml
- Weitere Details:
- Ca2+-binding protein that plays a key role in store-operated Ca2+entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca2+resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human CRACR2A
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-cracr2a_polyclonal_antibody-e_ab_19269