GSKIP Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-18894-20UL
60 ul
£183,00
E-AB-18894-60UL
120 ul
£272,00
E-AB-18894-120UL
200 ul
£420,00
E-AB-18894-200UL
Über dieses Produkt
- SKU:
- E-AB-18894
- Zusätzliche Namen:
- C14ORF129;Chromosome 14 open reading frame 129 ;GSK3-beta interaction protein;GSK3beta interaction protein;GSKIP;MGC4945;UPF0279
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.96 mg/ml
- Weitere Details:
- This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human GSKIP
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-gskip_polyclonal_antibody-e_ab_18894