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Antikörper

RNF111 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-18773-20UL
60 ul
£183,00
E-AB-18773-60UL
120 ul
£272,00
E-AB-18773-120UL
200 ul
£420,00
E-AB-18773-200UL
Über dieses Produkt
SKU:
E-AB-18773
Zusätzliche Namen:
ARK,Arkadia,DKFZp313E0731,DKFZp686H1966,DKFZp761D081,E3 ubiquitin protein ligase Arkadia,E3 ubiquitin-protein ligase Arkadia,FLJ38008,RING finger protein 111,RN111,RNF 111,RNF111
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
0.84 mg/ml
Weitere Details:
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase.This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription.As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development.Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Host:
Rabbit
Immunogen:
Fusion protein of human RNF111
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody