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Antikörper

CHRD Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-18617-20UL
60 ul
£183,00
E-AB-18617-60UL
120 ul
£272,00
E-AB-18617-120UL
200 ul
£420,00
E-AB-18617-200UL
Über dieses Produkt
SKU:
E-AB-18617
Zusätzliche Namen:
CHRD;Chordin;MGC133038;SOG;Shortgastrulation protein;chrd
Anwendung:
Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.8 mg/ml
Weitere Details:
CHRD (Chordin) is a Protein Coding gene. Diseases associated with CHRD include Cornelia De Lange Syndrome. Among its related pathways are Mesodermal Commitment Pathway and TGF-beta signaling pathway (KEGG). GO annotations related to this gene include heparin binding and syndecan binding. An important paralog of this gene is CHRDL2.This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that this gene could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of this gene results in enhanced bone regeneration. Alternative splicing results in multiple transcript variants. Other alternative splice variants have been described but their full length sequence has not been determined.
Host:
Rabbit
Immunogen:
Fusion protein of human CHRD
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody