TPPP Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-18394-20UL
60 ul
£183,00
E-AB-18394-60UL
120 ul
£272,00
E-AB-18394-120UL
200 ul
£420,00
E-AB-18394-200UL
Über dieses Produkt
- SKU:
- E-AB-18394
- Zusätzliche Namen:
- 25 kDa brain specific protein ,25 kDa brain-specific protein,Brain specific protein p25 alpha,Glycogen synthase kinase 3 (GSK3) inhibitor p24,OTTHUMP00000161630,TPPP,TPPP/p25,TPPP1,Tubulin polymerization promoting protein,p24,p25,p25-alpha,p25alpha
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.8 mg/ml
- Weitere Details:
- Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
- Host:
- Rabbit
- Immunogen:
- Full length fusion protein
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-tppp_polyclonal_antibody-e_ab_18394