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Antikörper

ATF6B Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-18330-20UL
60 ul
£183,00
E-AB-18330-60UL
120 ul
£272,00
E-AB-18330-120UL
200 ul
£420,00
E-AB-18330-200UL
Über dieses Produkt
SKU:
E-AB-18330
Zusätzliche Namen:
ATF6-beta;ATF6B;Activating transcription factor 6 beta;CREBL1;Cyclic AMP-dependent transcription factor ATF-6 beta;G13;Protein G13;cAMP response element-binding protein-related protein;cAMP-dependent transcription factor ATF-6 beta
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Fusion protein of human ATF6B
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody