CAPN6 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-18214-20UL
60 ul
£183,00
E-AB-18214-60UL
120 ul
£272,00
E-AB-18214-120UL
200 ul
£420,00
E-AB-18214-200UL
Über dieses Produkt
- SKU:
- E-AB-18214
- Zusätzliche Namen:
- CALP M;CAN6;CANP X;CANPX;CAPN 6;CalpM;Calpain-6;Calpain-like protease X-linked;Calpamodulin;Capn6
- Anwendung:
- Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.78 mg/ml
- Weitere Details:
- Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human CAPN6
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-capn6_polyclonal_antibody-e_ab_18214