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Antikörper

GFI1 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-17997-20UL
60 ul
£183,00
E-AB-17997-60UL
120 ul
£272,00
E-AB-17997-120UL
200 ul
£420,00
E-AB-17997-200UL
Über dieses Produkt
SKU:
E-AB-17997
Zusätzliche Namen:
GFI 1;GFI1;Growth factor independence 1;Growth factor independent 1;Growth factor independent protein 1;SCN2;ZNF 163;ZNF163;Zinc finger protein 163;Zinc finger protein Gfi 1;Zinc finger protein Gfi-1;Zinc finger protein Gfi1
Anwendung:
Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
1.62 mg/ml
Weitere Details:
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
Host:
Rabbit
Immunogen:
Synthetic peptide of human GFI1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody