ELANE Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-17904-20UL
60 ul
£183,00
E-AB-17904-60UL
120 ul
£272,00
E-AB-17904-120UL
200 ul
£420,00
E-AB-17904-200UL
Über dieses Produkt
- SKU:
- E-AB-17904
- Zusätzliche Namen:
- Bone marrow serine protease;ELA2;ELANE;ELNE;Elastase 2;Elastase 2 neutrophil ;Elastase neutrophil expressed;Elastase-2;GE;Granulocyte derived elastase;HLE;HNE;Human leukocyte elastase;Leukocyte elastase;Medullasin;NE;Neutrophil elastase;PMN E;PMN elastase
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.9 mg/ml
- Weitere Details:
- Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ELANE
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-elane_polyclonal_antibody-e_ab_17904