CARD16 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-17810-20UL
60 ul
£183,00
E-AB-17810-60UL
120 ul
£272,00
E-AB-17810-120UL
200 ul
£420,00
E-AB-17810-200UL
Über dieses Produkt
- SKU:
- E-AB-17810
- Zusätzliche Namen:
- member 16;CAR16;CARD only domain-containing protein 1;CARD only protein ;CARD16;COP;COP1;Caspase recruitment domain family;Caspase recruitment domain-containing protein 16;Caspase-1 dominant-negative inhibitor pseudo-ICE ;Caspase-1 inhibitor COP;Pseudo i
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1.1 mg/ml
- Weitere Details:
- Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CARD16
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-card16_polyclonal_antibody-e_ab_17810