C14orf169 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-17743-20UL
60 ul
£183,00
E-AB-17743-60UL
120 ul
£272,00
E-AB-17743-120UL
200 ul
£420,00
E-AB-17743-200UL
Über dieses Produkt
- SKU:
- E-AB-17743
- Zusätzliche Namen:
- 60S ribosomal protein L8 histidine hydroxylase;C14orf169;Chromosome 14 open reading frame 169 ;Histone lysine demethylase NO66;Hypothetical protein FLJ21802;Lysine-specific demethylase NO66;MAPJD;MYC associated protein with JmjC domain;NO66;Nu;hsNO66
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.8 mg/ml
- Weitere Details:
- Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Participates in MYC-induced transcriptional activation.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human C14orf169
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-c14orf169_polyclonal_antibody-e_ab_17743