TXNIP Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-17496-20UL
60 ul
£183,00
E-AB-17496-60UL
120 ul
£272,00
E-AB-17496-120UL
200 ul
£420,00
E-AB-17496-200UL
Über dieses Produkt
- SKU:
- E-AB-17496
- Zusätzliche Namen:
- EST01027,HHCPA78,THIF,VDUP1
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1.9 mg/ml
- Weitere Details:
- May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human TXNIP
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-txnip_polyclonal_antibody-e_ab_17496