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Antikörper

TTI1 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-17482-20UL
60 ul
£183,00
E-AB-17482-60UL
120 ul
£272,00
E-AB-17482-120UL
200 ul
£420,00
E-AB-17482-200UL
Über dieses Produkt
SKU:
E-AB-17482
Zusätzliche Namen:
KIAA0406,smg-10
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1.2 mg/ml
Weitere Details:
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
Host:
Rabbit
Immunogen:
Synthetic peptide of human TTI1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody