GAD1 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-17390-20UL
60 ul
£183,00
E-AB-17390-60UL
120 ul
£272,00
E-AB-17390-120UL
200 ul
£420,00
E-AB-17390-200UL
Über dieses Produkt
- SKU:
- E-AB-17390
- Zusätzliche Namen:
- 67 kDa glutamic acid decarboxylase;67kDa);CPSQ1;DCE1;EC 4.1.1.15;FLJ45882;GAD;GAD 67;GAD-67;GAD1;Glutamate decarboxy;Glutamate decarboxylase 1;Glutamate decarboxylase 1 (brain;Glutamate decarboxylase 1 brain 67kD;Glutamate decarboxylase 1 brain 67kDa
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human GAD1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-gad1_polyclonal_antibody-e_ab_17390