ABCC2 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-17352-20UL
60 ul
£183,00
E-AB-17352-60UL
120 ul
£272,00
E-AB-17352-120UL
200 ul
£420,00
E-AB-17352-200UL
Über dieses Produkt
- SKU:
- E-AB-17352
- Zusätzliche Namen:
- ABC30;ATP binding cassette sub family C (CFTR/MRP) member 2;ATP binding cassette subfamily C member 2;ATP-binding cassette sub-family C member 2;CMO;CMOAT;Canalicular multidrug resistance protein;Canalicular multispecific organic anion transporter 1;abcC2
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ABCC2
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-abcc2_polyclonal_antibody-e_ab_17352