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Antikörper

KCNQ4 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-16544-20UL
60 ul
£183,00
E-AB-16544-60UL
120 ul
£272,00
E-AB-16544-120UL
200 ul
£420,00
E-AB-16544-200UL
Über dieses Produkt
SKU:
E-AB-16544
Zusätzliche Namen:
DFNA 2,DFNA2,KCNQ 4,KCNQ4,KQT like 4,KQT-like 4,KV7.4,Kcnq4,Potassium channel KQT like 4,Potassium channel subunit alpha KvLQT4,Potassium voltag,Potassium voltage gated channel KQT like protein 4,Potassium voltage gated channel KQT like subfamily member 4
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
0.9 mg/ml
Weitere Details:
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Synthetic peptide of human KCNQ4
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody