EMP2 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-16404-20UL
60 ul
£183,00
E-AB-16404-60UL
120 ul
£272,00
E-AB-16404-120UL
200 ul
£420,00
E-AB-16404-200UL
Über dieses Produkt
- SKU:
- E-AB-16404
- Zusätzliche Namen:
- EMP 2;EMP-2;EMP2;Epithelial membrane protein 2;Protein XMP
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.8 mg/ml
- Weitere Details:
- EMP-2 (epithelial membrane protein 2), also known as XMP, is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human EMP2
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-emp2_polyclonal_antibody-e_ab_16404