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Antikörper

CD54 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-16322-20UL
60 ul
£183,00
E-AB-16322-60UL
120 ul
£272,00
E-AB-16322-120UL
200 ul
£420,00
E-AB-16322-200UL
Über dieses Produkt
SKU:
E-AB-16322
Zusätzliche Namen:
Antigen identified by monoclonal BB2,BB 2,BB2,CD 54,CD54,CD_antigen=CD54,Cell surface glycoprotein P3.58,Human rhinovirus receptor,ICAM 1,ICAM-1,ICAM1,Intercellular adhesion molecule,human rhinovirus receptor,intercellular adhesion molecule 1 (CD54)
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
0.4 mg/ml
Weitere Details:
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Host:
Rabbit
Immunogen:
Synthetic peptide of human ICAM1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody