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Antikörper

BLNK Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-16280-20UL
60 ul
£183,00
E-AB-16280-60UL
120 ul
£272,00
E-AB-16280-120UL
200 ul
£420,00
E-AB-16280-200UL
Über dieses Produkt
SKU:
E-AB-16280
Zusätzliche Namen:
AGM4;B cell adapter containing SH2 domain protein;B cell adapter containing Src homology 2 domain protein;B cell adaptor containing SH2 domain;B cell linker;B cell linker protein;B cell-specific adaptor protein;B-cell activation;B-cell adapter containing
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.6 mg/ml
Weitere Details:
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.
Host:
Rabbit
Immunogen:
Synthetic peptide of human BLNK
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody