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Antikörper

MANF Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-16174-20UL
60 ul
£183,00
E-AB-16174-60UL
120 ul
£272,00
E-AB-16174-120UL
200 ul
£420,00
E-AB-16174-200UL
Über dieses Produkt
SKU:
E-AB-16174
Zusätzliche Namen:
ARMET,ARMET protein,ARP,Arginine rich mutated in early stage tumors,Arginine rich protein,Arginine-rich protein,MANF,MGC142148,MGC142150,Manf,Mesencephalic astrocyte derived neurotrophic factor,Mesencephalic astrocyte-derived neurotrophic factor,Protein A
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
0.4 mg/ml
Weitere Details:
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Host:
Rabbit
Immunogen:
Synthetic peptide of human MANF
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody