Factor XIIIa Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-16093-20UL
60 ul
£183,00
E-AB-16093-60UL
120 ul
£272,00
E-AB-16093-120UL
200 ul
£420,00
E-AB-16093-200UL
Über dieses Produkt
- SKU:
- E-AB-16093
- Zusätzliche Namen:
- A polypeptide;A1 polypeptide);Coagulation factor XIII;Coagulation factor XIII A chain;Coagulation factor XIII A1 polypeptide;Coagulation factor XIII A1 subunit;Coagulation factor XIIIa;F13A;F13a1;Factor XIIIA;Fibri;bA525O21.1 (coagulation factor XIII
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.7 mg/ml
- Weitere Details:
- This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human F13A1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-factor_xiiia_polyclonal_antibody-e_ab_16093