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Antikörper

LATS2 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-15942-20UL
60 ul
£183,00
E-AB-15942-60UL
120 ul
£272,00
E-AB-15942-120UL
200 ul
£420,00
E-AB-15942-200UL
Über dieses Produkt
SKU:
E-AB-15942
Zusätzliche Namen:
FLJ13161,KPM,Kinase phosphorylated during mitosis protein,L,LATS large tumor suppressor Drosophila homolog 2,LATS large tumor suppressor homolog 2,Large tumor suppressor homolog 2,Large tumor suppressor homolog 2 Drosophila,Large tumor suppressor kinase 2
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
Host:
Rabbit
Immunogen:
Synthetic peptide of human LATS2
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody