SPAG1 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-15858-20UL
60 ul
£183,00
E-AB-15858-60UL
120 ul
£272,00
E-AB-15858-120UL
200 ul
£420,00
E-AB-15858-200UL
Über dieses Produkt
- SKU:
- E-AB-15858
- Zusätzliche Namen:
- CILD28,FLJ32920,HSD-3.8,Infertility related sperm protein Spag 1,SP75,SPAG1,Sperm associated antigen 1,TPIS,TPR containing protein involved in spermatogenesis,Tetratricopeptide repeat-containing protein
- Anwendung:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.3 mg/ml
- Weitere Details:
- The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human SPAG1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-spag1_polyclonal_antibody-e_ab_15858