SMAD7 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-15853-20UL
60 ul
£183,00
E-AB-15853-60UL
120 ul
£272,00
E-AB-15853-120UL
200 ul
£420,00
E-AB-15853-200UL
Über dieses Produkt
- SKU:
- E-AB-15853
- Zusätzliche Namen:
- CRCS3,FLJ16482,MAD,MAD (mothers against decapentaplegic Drosophila) homolog 7,MAD homolog 8,MAD mothers against decapentaplegic homolog 7,MADH 7,MADH 8,MADH6,MADH8,Mad homolog 7,Mother,Mothers Against Decapentaplegic Drosophila Homolog of 6,hSMAD 7,hSMAD7
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.4 mg/ml
- Weitere Details:
- The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human SMAD7
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-smad7_polyclonal_antibody-e_ab_15853