HMGB1 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-15716-20UL
60 ul
£183,00
E-AB-15716-60UL
120 ul
£272,00
E-AB-15716-120UL
200 ul
£420,00
E-AB-15716-200UL
Über dieses Produkt
- SKU:
- E-AB-15716
- Zusätzliche Namen:
- Amphoterin;Chromosomal protein;DKFZp686A04236;HMG-1;HMG1;HMG3;HMGB 1;HMGB1;High mobility group 1;High mobility group box 1;High mobility group protein 1;High mobility group protein B1;high-mobility group (nonhistone chromosomal) protein 1;nonhistone
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.3 mg/ml
- Weitere Details:
- High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFB family, ATF-2 and c-Jun to activate transcription. Other studies indicate that phosphorylation of HMG protein is required to stimulate the transcriptional activity of the protein. Human HMG-1 and HMG-2 both contain two DNA-binding domains, termed HMG boxes. HMG proteins bind single-stranded DNA but induce conformational changes in double-stranded DNA alone.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human HMGB1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-hmgb1_polyclonal_antibody-e_ab_15716