GRK1 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-15702-20UL
60 ul
£183,00
E-AB-15702-60UL
120 ul
£272,00
E-AB-15702-120UL
200 ul
£420,00
E-AB-15702-200UL
Über dieses Produkt
- SKU:
- E-AB-15702
- Zusätzliche Namen:
- GPRK1;RHOK;RK
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human GRK1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-grk1_polyclonal_antibody-e_ab_15702