SLC1A6 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-15608-20UL
60 ul
£183,00
E-AB-15608-60UL
120 ul
£272,00
E-AB-15608-120UL
200 ul
£420,00
E-AB-15608-200UL
Über dieses Produkt
- SKU:
- E-AB-15608
- Zusätzliche Namen:
- Excitatory amino acid transporter 4,High affinity neuronal glutamate transporter,MGC33092,MGC43671,Sodium dependent glutamate/aspartate transporter,Solute carrier family 1 (high affinity aspartate/glutamate transporter) member 6,Solute carrier family 1 me
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.4 mg/ml
- Weitere Details:
- Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human SLC1A6
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-slc1a6_polyclonal_antibody-e_ab_15608