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Antikörper

SEMA4A Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-15382-20UL
60 ul
£183,00
E-AB-15382-60UL
120 ul
£272,00
E-AB-15382-120UL
200 ul
£420,00
E-AB-15382-200UL
Über dieses Produkt
SKU:
E-AB-15382
Zusätzliche Namen:
CORD10,RP11 54H19 2,RP35,SEM4A,Sema B,Sema domain,Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain 4A,Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4A,immunogl
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
0.8 mg/ml
Weitere Details:
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Host:
Rabbit
Immunogen:
Recombinant protein of human SEMA4A
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody