HSP40-4 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-15115-20UL
60 ul
£183,00
E-AB-15115-60UL
120 ul
£272,00
E-AB-15115-120UL
200 ul
£420,00
E-AB-15115-200UL
Über dieses Produkt
- SKU:
- E-AB-15115
- Zusätzliche Namen:
- DJ 2;DJ2;DNAJ2;DNJA1;DjA1;DnaJ (Hsp40) homolog;DnaJ homolog subfamily A member 1;DnaJ protein homolog 2;Dnaja1;HDJ-2;HDJ2;HSDJ;HSJ-2;HSJ2;HSPF4;Heat shock 40 kDa protein 4;Heat shock protein J2;Hum;hDJ 2;heat shock protein DNAJ like 2;member 1;subfamily A
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human DNAJA1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-hsp40_4_polyclonal_antibody-e_ab_15115