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Antikörper

GADD45B Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-15054-20UL
60 ul
£183,00
E-AB-15054-60UL
120 ul
£272,00
E-AB-15054-120UL
200 ul
£420,00
E-AB-15054-200UL
Über dieses Produkt
SKU:
E-AB-15054
Zusätzliche Namen:
GA45B;GADD45 Beta;GADD45BETA;Gadd45b;Growth arres;Growth arrest and DNA damage inducible 45 beta;Growth arrest and DNA damage inducible beta;Growth arrest and DNA damage-inducible gene GADD45;Growth arrest and DNA damage-inducible protein GADD45 beta;beta
Anwendung:
Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.6 mg/ml
Weitere Details:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
Host:
Rabbit
Immunogen:
Recombinant protein of human GADD45B
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody