KCNJ11 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-14986-20UL
60 ul
£183,00
E-AB-14986-60UL
120 ul
£272,00
E-AB-14986-120UL
200 ul
£420,00
E-AB-14986-200UL
Über dieses Produkt
- SKU:
- E-AB-14986
- Zusätzliche Namen:
- ATP sensitive inward rectifier potassium channel 11,BIR,Beta cell inward rectifier subunit,HHF 2,HHF2,IKATP,IRK 11,IRK11,Inward rectifier K(+) channel Kir6.2,Inwardly rectifying potassium channel KIR6.2,KCNJ11,Kir 6.2,Kir6.2,MGC133230,PHHI,Potassium chann
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.7 mg/ml
- Weitere Details:
- Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human KCNJ11
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-kcnj11_polyclonal_antibody-e_ab_14986