EID1 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-14978-20UL
60 ul
£183,00
E-AB-14978-60UL
120 ul
£272,00
E-AB-14978-120UL
200 ul
£420,00
E-AB-14978-200UL
Über dieses Produkt
- SKU:
- E-AB-14978
- Zusätzliche Namen:
- 21 kDa pRb associated protein;21 kDa pRb-associated protein;C15orf3;CBP;CREBBP/EP300 inhibitor 1;CREBBP/EP300 inhibitory protein 1;CRI 1;CRI1;Chromosome 15 open reading frame 3;E1A like inhibitor of differentiation;E1A-like inhibitor of differentiation 1
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human EID1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-eid1_polyclonal_antibody-e_ab_14978