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Antikörper

CRK Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-14896-20UL
60 ul
£183,00
E-AB-14896-60UL
120 ul
£272,00
E-AB-14896-120UL
200 ul
£420,00
E-AB-14896-200UL
Über dieses Produkt
SKU:
E-AB-14896
Zusätzliche Namen:
Adapter molecule crk;Avian sarcoma virus CT10 (v crk) oncogene homolog;CRK;CRK isoform 2;CRK isoform II;CRKII;FLJ38130;OTTHUMP00000115366;OTTHUMP00000198330;Proto oncogene C crk;Proto-oncogene C-crk;p38;v crk avian sarcoma virus CT10 oncogene homolog
Anwendung:
Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.4 mg/ml
Weitere Details:
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Host:
Rabbit
Immunogen:
Recombinant protein of human CRK
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody