DOK4 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-14690-20UL
60 ul
£183,00
E-AB-14690-60UL
120 ul
£272,00
E-AB-14690-120UL
200 ul
£420,00
E-AB-14690-200UL
Über dieses Produkt
- SKU:
- E-AB-14690
- Zusätzliche Namen:
- Downstream of tyrosine kinase 4,FLJ10488,IRS5,docking protein 4,insulin receptor substrate 5
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- Docking protein 4 is a protein that in humans is encoded by the DOK4 gene.Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins.Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation.Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation.Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human DOK4
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-dok4_polyclonal_antibody-e_ab_14690