DOK4 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-14690-20UL
60 ul
£183,00
E-AB-14690-60UL
120 ul
£272,00
E-AB-14690-120UL
200 ul
£420,00
E-AB-14690-200UL
Über dieses Produkt
- SKU:
- E-AB-14690
- Zusätzliche Namen:
- Downstream of tyrosine kinase 4;FLJ10488;IRS5;docking protein 4;insulin receptor substrate 5
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- Docking protein 4is aproteinthat in humans is encoded by theDOK4gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human DOK4
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-dok4_polyclonal_antibody-e_ab_14690