ERG Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-14117-20UL
60 ul
£183,00
E-AB-14117-60UL
120 ul
£272,00
E-AB-14117-120UL
200 ul
£420,00
E-AB-14117-200UL
Über dieses Produkt
- SKU:
- E-AB-14117
- Zusätzliche Namen:
- Avian erythroblastosis virus E-26 (v-ets) oncogene related;D030036I24Rik;ERG;ERG/EWS fusion gene;ERG/FUS fusion gene;ERG/TMPSSR2 fusion gene;ERG1;ERG2;ETS-related gene;Erg;Erg 3;KCNH2;Oncogene ERG;ets related;included;p
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.4 mg/ml
- Weitere Details:
- This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human ERG
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-erg_polyclonal_antibody-e_ab_14117