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Antikörper

GREM1 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-14111-20UL
60 ul
£183,00
E-AB-14111-60UL
120 ul
£272,00
E-AB-14111-120UL
200 ul
£420,00
E-AB-14111-200UL
Über dieses Produkt
SKU:
E-AB-14111
Zusätzliche Namen:
BMP antagonist 1;CKTSF1B1;Cell proliferation inducing gene 2 protein;Cell proliferation-inducing gene 2 protein;Cysteine knot superfamily 1;Cysteine knot superfamily BMP antag;colorectal adenoma and carcinoma 1
Anwendung:
Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.3 mg/ml
Weitere Details:
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human GREM1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody