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Antikörper

CDC27 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-13987-20UL
60 ul
£183,00
E-AB-13987-60UL
120 ul
£272,00
E-AB-13987-120UL
200 ul
£420,00
E-AB-13987-200UL
Über dieses Produkt
SKU:
E-AB-13987
Zusätzliche Namen:
ANAPC3;APC 3;APC3;Anaphase Promoting Complex 3;Anaphase Promoting Complex Subunit 3;Anaphase promoting complex protein 3;Anaphase-promoting complex subunit 3;CDC27;CDC27 homolog;CDC27Hs;Cdc 27;Cdc27;Cell Division Cycle 27;Cell division cycle protein 27 ho
Anwendung:
Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.3 mg/ml
Weitere Details:
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human CDC27
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody