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Antikörper

Amphiphysin II Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-13951-20UL
60 ul
£183,00
E-AB-13951-60UL
120 ul
£272,00
E-AB-13951-120UL
200 ul
£420,00
E-AB-13951-200UL
Über dieses Produkt
SKU:
E-AB-13951
Zusätzliche Namen:
AMPH 2;AMPH2;AMPHL;Amphiphysin 2;Amphiphysin II;Amphiphysin like protein;Amphiphysin-like protein;BIN1;Bin1;Box Dependant MYC Interacting Protein 1;Box-dependent myc-interacting protein 1;Bridging integrator 1;DKFZp547F068;MGC10367;MGC105;amphiphysin-like
Anwendung:
Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.1 mg/ml
Weitere Details:
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Host:
Rabbit
Immunogen:
Recombinant protein of human BIN1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody