HIF1AN Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-13556-20UL
60 ul
£183,00
E-AB-13556-60UL
120 ul
£272,00
E-AB-13556-120UL
200 ul
£420,00
E-AB-13556-200UL
Über dieses Produkt
- SKU:
- E-AB-13556
- Zusätzliche Namen:
- DKFZp762F1811;FIH 1;FIH-1;FIH1;FLJ20615;FLJ22027 ;Factor inhibiting HIF-1;Factor inhibiting HIF1;HIF1AN;HIF1N;Hyp;Hypoxia inducible factor 1 alpha inhibitor;Hypoxia inducible factor 1 alpha subunit inhibitor;Hypoxia inducible factor asparagine hydroxylase
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the beta-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1alpha. This hydroxylation event blocks the association of HIF-1alpha with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1alpha. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human HIF1AN
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-hif1an_polyclonal_antibody-e_ab_13556