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Antikörper

HSD17B1 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-13312-20UL
60 ul
£183,00
E-AB-13312-60UL
120 ul
£272,00
E-AB-13312-120UL
200 ul
£420,00
E-AB-13312-200UL
Über dieses Produkt
SKU:
E-AB-13312
Zusätzliche Namen:
17 beta HSD 1;17 beta hydroxysteroid dehydrogenase type 1;17-beta-HSD 1;17-beta-hydroxysteroid dehydrogenase type 1;20 alpha-hydroxysteroid dehydrogenase;20-alpha-HSD;DHB1;E17KSR;E2DH;EDH17B1;EDH17B2;EDHB17;Estradiol 17 beta dehydrogenase 1;Estradiol 17-b
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.9 mg/ml
Weitere Details:
Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.
Host:
Rabbit
Immunogen:
Synthetic peptide of human HSD17B1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody