HSD11B2 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-13311-20UL
60 ul
£183,00
E-AB-13311-60UL
120 ul
£272,00
E-AB-13311-120UL
200 ul
£420,00
E-AB-13311-200UL
Über dieses Produkt
- SKU:
- E-AB-13311
- Zusätzliche Namen:
- 11 DH2;11 beta HSD2;11 beta hydroxysteroid dehydrogenase type 2;11-DH2;11-beta-HSD2;11-beta-hydroxysteroid dehydrogenase type 2;AME;AME1;Corticosteroid 11 beta dehydrogenase isozyme 2;Corticosteroid 11-beta-dehydrogenase isozyme 2;DHI2;HSD11B2;HSD11K;HSD2
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.6 mg/ml
- Weitere Details:
- There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human HSD11B2
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-hsd11b2_polyclonal_antibody-e_ab_13311