PTPN13 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-13236-20UL
60 ul
£183,00
E-AB-13236-60UL
120 ul
£272,00
E-AB-13236-120UL
200 ul
£420,00
E-AB-13236-200UL
Über dieses Produkt
- SKU:
- E-AB-13236
- Zusätzliche Namen:
- APO1/CD95 (Fas) associated phosphatase,DKFZp686J1497,FAP 1,FAP1,Fas associated phosphatase 1,Fas associated protein tyrosine phosphatase 1,HGNC:9646,PNP 1,PNP1,Phosphatase rip,Protein tyrosine phosphatase 1 Fas associated,hPTPE1,protein tyrosine phosphata
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human PTPN13
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-ptpn13_polyclonal_antibody-e_ab_13236