FZD6 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-12926-20UL
60 ul
£183,00
E-AB-12926-60UL
120 ul
£272,00
E-AB-12926-120UL
200 ul
£420,00
E-AB-12926-200UL
Über dieses Produkt
- SKU:
- E-AB-12926
- Zusätzliche Namen:
- FZD 6;FZD6;Frizzled 6 seven transmembrane spanning receptor;Frizzled drosophila homolog of 6;Frizzled family receptor 6;Frizzled homolog 6;Frizzled homolog 6 (Drosophila);Frizzled-6;Frizzled6;Fz 6;Fz-6;Fz6;Fzd6;Hfz 6;NDNC10;hFz6
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human FZD6
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-fzd6_polyclonal_antibody-e_ab_12926