TERT Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-12901-20UL
60 ul
£183,00
E-AB-12901-60UL
120 ul
£272,00
E-AB-12901-120UL
200 ul
£420,00
E-AB-12901-200UL
Über dieses Produkt
- SKU:
- E-AB-12901
- Zusätzliche Namen:
- CMM9,DKCA2,DKCB4,EST2,HEST2,PFBMFT1,TCS1,TERT,TP2,TRT,Telomerase associated protein 2,Telomerase catalytic subunit,Telomerase reverse transcriptase,Telomerase-associated protein 2,Telomere Reverse Transcriptase,hTRT,htert
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.4 mg/ml
- Weitere Details:
- Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified, the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human TERT
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-tert_polyclonal_antibody-e_ab_12901