MDC1 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-12802-20UL
60 ul
£183,00
E-AB-12802-60UL
120 ul
£272,00
E-AB-12802-120UL
200 ul
£420,00
E-AB-12802-200UL
Über dieses Produkt
- SKU:
- E-AB-12802
- Zusätzliche Namen:
- Homologue to Drosophila photoreceptor protein calphotin,MDC 1,MDC1,Mdc1,Mediation of DNA damage checkpoint 1,Mediator of DNA damage checkpoint 1,Mediator of DNA damage checkpoint protein 1,NFBD 1,NFBD1,Nuclear Factor wit,Nuclear factor with BRCT domains 1
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1.2 mg/ml
- Weitere Details:
- The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human MDC1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-mdc1_polyclonal_antibody-e_ab_12802