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Antikörper

MYSM1 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-12793-20UL
60 ul
£183,00
E-AB-12793-60UL
120 ul
£272,00
E-AB-12793-120UL
200 ul
£420,00
E-AB-12793-200UL
Über dieses Produkt
SKU:
E-AB-12793
Zusätzliche Namen:
2A-DUB,2ADUB,Histone H2A deubiquitinase,Histone H2A deubiquitinase MYSM1,KIAA1915,MYS,MYSM 1,Myb like,Myb like SWIRM and MPN domains 1,Myb-like,SWIRM and MPN domain containing protein,SWIRM and MPN domains 1,mysm1
Anwendung:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones
Host:
Rabbit
Immunogen:
Synthetic peptide of human MYSM1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody