DSP Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-12373-20UL
60 ul
£183,00
E-AB-12373-60UL
120 ul
£272,00
E-AB-12373-120UL
200 ul
£420,00
E-AB-12373-200UL
Über dieses Produkt
- SKU:
- E-AB-12373
- Zusätzliche Namen:
- 250/210 kDa paraneoplastic pemphigus antigen;DCWHKTA;DESP;DP;DP I;DP II;DPI;DPII;DSP;Desmoplakin;Desmoplakin (DPI DPII);Desmoplakin I;Desmoplakin II;KPPS2;PPKS 2;PPKS2
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human DSP
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-dsp_polyclonal_antibody-e_ab_12373