ABI1 Polyclonal Antibody
Produktgrößen
20 ul
£118,00
E-AB-12222-20UL
60 ul
£183,00
E-AB-12222-60UL
120 ul
£272,00
E-AB-12222-120UL
200 ul
£420,00
E-AB-12222-200UL
Über dieses Produkt
- SKU:
- E-AB-12222
- Zusätzliche Namen:
- ABI1;Abelson interactor 1;Abi-1;Abi1;Abl binding protein 4;Abl interactor 1;Abl interactor protein 1;Abl-binding protein 4;AblBP4;Eps8 SH3 domain binding protein;Eps8 SH3 domain-binding protein;Eps8 binding protein;Eps8-binding protein;Hssh3bp1;Inter;e3B1
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ABI1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-abi1_polyclonal_antibody-e_ab_12222