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Antikörper

PLEKHG6 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-11416-20UL
60 ul
£183,00
E-AB-11416-60UL
120 ul
£272,00
E-AB-11416-120UL
200 ul
£420,00
E-AB-11416-200UL
Über dieses Produkt
SKU:
E-AB-11416
Zusätzliche Namen:
FLJ10665,MGC126315,MGC126353,MGC126354,Myosin interacting guanine nucleotide exchange factor,PH domain containing family G member 6,Pleckstrin homology domain containing family G (with RhoGef domain) member 6,Pleckstrin homology domain-containing family G
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
0.4 mg/ml
Weitere Details:
PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
Host:
Rabbit
Immunogen:
Recombinant protein of human PLEKHG6
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody