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Antikörper

MRE11 Polyclonal Antibody

Produktgrößen
20 ul
£118,00
E-AB-11403-20UL
60 ul
£183,00
E-AB-11403-60UL
120 ul
£272,00
E-AB-11403-120UL
200 ul
£420,00
E-AB-11403-200UL
Über dieses Produkt
SKU:
E-AB-11403
Zusätzliche Namen:
AT like disease,ATLD,Ataxia telangiectasia disorder like,DNA recombination and repair protein,Double strand break repair protein MRE11A,Double-strand break repair protein MRE11A,HNGS1,endo/exonuclease Mre11,meiotic recombination (S. cerevisiae) 11 homolog
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
0.6 mg/ml
Weitere Details:
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Host:
Rabbit
Immunogen:
Recombinant protein of human MRE11A
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody